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📙 Biotechnology: Measuring, Modelling, and Control, Volume 4, Second Edition by — pdf free


This volume covers monitoring of the biotechnological process with sophisticated analytical techniques, use of the resulting data by means of mathematical models, and computer-aided control for improvement of the productivity of biotechnological processes.
The book consists of four main parts: instruments for analysis and biosensoring, measuring techniques, process models and their automation and control. The use of different cell types, recombinant microorganisms, and reactor conditions are presented and all present strategies of monitoring and optimizing cell growth and product formation are discussed with regard to improved productivity.
Topics included are: Methods and Instruments/ Biosensors/ Characterization of Bioreactors/ Determination of Cell Concentration/ Cell Models/ Stirred Tank Models/ Tower Reactor Models/ Process Models/ Control of Bioreactor Systems/ Automation/ Control of Downstream Processing

Content:
Chapter 1 Common Instruments for Process Analysis and Control (pages 4–25): Karl Schugerl
Chapter 2 Methods and Instruments in Fermentation Gas Analysis (pages 27–74): Elmar Heinzle and Irving J. Dunn
Chapter 3 Biosensors (pages 75–103): Bo Mattiasson
Chapter 4 Characterization of Bioreactors (pages 107–148): Andreas Lubbert
Chapter 5 On?Line Analysis of Broth (pages 149–178): Karl Schugerl
Chapter 6 Determination of Cell Concentration and Characterization of Cells (pages 179–223): Kenneth F. Reardon and Thomas H. Scheper
Chapter 7 Bioreactor State Estimation (pages 225–249): Gregory Stephanopoulos and Seujeung Park
Chapter 8 Optimization of Sampling (pages 251–264): Axel Munack
Chapter 9 Cell Models (pages 267–298): Karl?Heinz Bellgardt
Chapter 10 Stirred Tank Models (pages 299–348): Matthias Reuss and Rakesh Bajpai
Chapter 11 Tower Reactor Models (pages 349–382): Jose C. Merchuk
Chapter 12 Process Models: Optimization of Yeast Production — A Case Study (pages 383–406): Karl?Heinz Bellgardt and Jingqi Yuan
Chapter 13 Aerobic Wastewater Process Models (pages 407–439): Graham F. Andrews
Chapter 14 Anaerobic Waste Water Process Models (pages 441–484): Dirk Schurbuscher and Christian Wandrey
Chapter 15 Bioprocess Kinetics and Modelling of Recombinant Fermentation (pages 485–505): Dewey D. Y. Ryu, Jeong?Yoon Kim and Sun Bok Lee
Chapter 16 Control of Bioreactor Systems (pages 509–560): Henry C. Lim and Kyu?Sung Lee
Chapter 17 Automation in Biotechnology (pages 561–602): Andreas Lubbert
Chapter 18 Modelling, Design, and Control of Downstream Processing (pages 603–623): Suteaki Shioya and Ken?Ichi Suga
Chapter 19 Expert Systems for Biotechnology (pages 625–636): Aarne Halme and Nazmul Karim

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