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This volume covers monitoring of the biotechnological process with sophisticated analytical techniques, use of the resulting data by means of mathematical models, and computer-aided control for improvement of the productivity of biotechnological processes.

The book consists of four main parts: instruments for analysis and biosensoring, measuring techniques, process models and their automation and control. The use of different cell types, recombinant microorganisms, and reactor conditions are presented and all present strategies of monitoring and optimizing cell growth and product formation are discussed with regard to improved productivity.

Topics included are: Methods and Instruments/ Biosensors/ Characterization of Bioreactors/ Determination of Cell Concentration/ Cell Models/ Stirred Tank Models/ Tower Reactor Models/ Process Models/ Control of Bioreactor Systems/ Automation/ Control of Downstream Processing

Content:

Chapter 1 Common Instruments for Process Analysis and Control (pages 4â€“25): Karl Schugerl

Chapter 2 Methods and Instruments in Fermentation Gas Analysis (pages 27â€“74): Elmar Heinzle and Irving J. Dunn

Chapter 3 Biosensors (pages 75â€“103): Bo Mattiasson

Chapter 4 Characterization of Bioreactors (pages 107â€“148): Andreas Lubbert

Chapter 5 On?Line Analysis of Broth (pages 149â€“178): Karl Schugerl

Chapter 6 Determination of Cell Concentration and Characterization of Cells (pages 179â€“223): Kenneth F. Reardon and Thomas H. Scheper

Chapter 7 Bioreactor State Estimation (pages 225â€“249): Gregory Stephanopoulos and Seujeung Park

Chapter 8 Optimization of Sampling (pages 251â€“264): Axel Munack

Chapter 9 Cell Models (pages 267â€“298): Karl?Heinz Bellgardt

Chapter 10 Stirred Tank Models (pages 299â€“348): Matthias Reuss and Rakesh Bajpai

Chapter 11 Tower Reactor Models (pages 349â€“382): Jose C. Merchuk

Chapter 12 Process Models: Optimization of Yeast Production â€” A Case Study (pages 383â€“406): Karl?Heinz Bellgardt and Jingqi Yuan

Chapter 13 Aerobic Wastewater Process Models (pages 407â€“439): Graham F. Andrews

Chapter 14 Anaerobic Waste Water Process Models (pages 441â€“484): Dirk Schurbuscher and Christian Wandrey

Chapter 15 Bioprocess Kinetics and Modelling of Recombinant Fermentation (pages 485â€“505): Dewey D. Y. Ryu, Jeong?Yoon Kim and Sun Bok Lee

Chapter 16 Control of Bioreactor Systems (pages 509â€“560): Henry C. Lim and Kyu?Sung Lee

Chapter 17 Automation in Biotechnology (pages 561â€“602): Andreas Lubbert

Chapter 18 Modelling, Design, and Control of Downstream Processing (pages 603â€“623): Suteaki Shioya and Ken?Ichi Suga

Chapter 19 Expert Systems for Biotechnology (pages 625â€“636): Aarne Halme and Nazmul Karim

## About book:

## About file:

Security code:

The book consists of four main parts: instruments for analysis and biosensoring, measuring techniques, process models and their automation and control. The use of different cell types, recombinant microorganisms, and reactor conditions are presented and all present strategies of monitoring and optimizing cell growth and product formation are discussed with regard to improved productivity.

Topics included are: Methods and Instruments/ Biosensors/ Characterization of Bioreactors/ Determination of Cell Concentration/ Cell Models/ Stirred Tank Models/ Tower Reactor Models/ Process Models/ Control of Bioreactor Systems/ Automation/ Control of Downstream Processing

Content:

Chapter 1 Common Instruments for Process Analysis and Control (pages 4â€“25): Karl Schugerl

Chapter 2 Methods and Instruments in Fermentation Gas Analysis (pages 27â€“74): Elmar Heinzle and Irving J. Dunn

Chapter 3 Biosensors (pages 75â€“103): Bo Mattiasson

Chapter 4 Characterization of Bioreactors (pages 107â€“148): Andreas Lubbert

Chapter 5 On?Line Analysis of Broth (pages 149â€“178): Karl Schugerl

Chapter 6 Determination of Cell Concentration and Characterization of Cells (pages 179â€“223): Kenneth F. Reardon and Thomas H. Scheper

Chapter 7 Bioreactor State Estimation (pages 225â€“249): Gregory Stephanopoulos and Seujeung Park

Chapter 8 Optimization of Sampling (pages 251â€“264): Axel Munack

Chapter 9 Cell Models (pages 267â€“298): Karl?Heinz Bellgardt

Chapter 10 Stirred Tank Models (pages 299â€“348): Matthias Reuss and Rakesh Bajpai

Chapter 11 Tower Reactor Models (pages 349â€“382): Jose C. Merchuk

Chapter 12 Process Models: Optimization of Yeast Production â€” A Case Study (pages 383â€“406): Karl?Heinz Bellgardt and Jingqi Yuan

Chapter 13 Aerobic Wastewater Process Models (pages 407â€“439): Graham F. Andrews

Chapter 14 Anaerobic Waste Water Process Models (pages 441â€“484): Dirk Schurbuscher and Christian Wandrey

Chapter 15 Bioprocess Kinetics and Modelling of Recombinant Fermentation (pages 485â€“505): Dewey D. Y. Ryu, Jeong?Yoon Kim and Sun Bok Lee

Chapter 16 Control of Bioreactor Systems (pages 509â€“560): Henry C. Lim and Kyu?Sung Lee

Chapter 17 Automation in Biotechnology (pages 561â€“602): Andreas Lubbert

Chapter 18 Modelling, Design, and Control of Downstream Processing (pages 603â€“623): Suteaki Shioya and Ken?Ichi Suga

Chapter 19 Expert Systems for Biotechnology (pages 625â€“636): Aarne Halme and Nazmul Karim

- Author:
- Year:
**1991** - Publisher:
**VCH Verlagsgesellschaft mbH** - Language:
**English** - ISBN:
**9783527283149,9783527620852**

- File size:
**10 112 673** - Format:
**pdf**

Security code:

At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now,...

At publication, The Control Handbook immediately became the definitive resource that engineers working with modern control systems required. Among its many accolades, that first edition was cited by the AAP as the Best Engineering Handbook of 1996. Now,...

Praise for the First Edition". . . a readable, comprehensive volume that . . . belongs on the desk, close at hand, of any serious researcher or practitioner." ?Mathematical Geosciences The state of the art in geostatistics Geostatistical models and techni...

Reflects the latest applied research and features state-of-the-art software for building and solving spreadsheet optimization modelsThoroughly updated to reflect the latest topical and technical advances in the field, Optimization Modeling with Spreadshee...

More than a decade ago, world-renowned control systems authority Frank L. Lewis introduced what would become a standard textbook on estimation, under the title Optimal Estimation, used in top universities throughout the world. The time has come for a new ...

Praise for the First Edition"This...novel and highly stimulating book, which emphasizes solving real problems...should be widely read. It will have a positive and lasting effect on the teaching of modeling and statistics in general." - Short Book ReviewsT...

Praise for the First Edition"This...novel and highly stimulating book, which emphasizes solving real problems...should be widely read. It will have a positive and lasting effect on the teaching of modeling and statistics in general." - Short Book ReviewsT...

Since John Bosch edited and published the first version of this book in 1995, the world of manufacturing and coordinate measuring machines (CMMs) and coordinate measuring systems (CMSs) has changed considerably. However, the basic physics of the machines ...

More than a decade ago, world-renowned control systems authority Frank L. Lewis introduced what would become a standard textbook on estimation, under the title Optimal Estimation, used in top universities throughout the world. The time has come for a new ...

Significantly revised and expanded, this authoritative reference/text comprehensively describes concepts in measure theory, classical integration, and generalized Riemann integration of both scalar and vector types-providing a complete and detailed review...