DMCA. Copyrighted Work that you can Claim.
Base have 820 524 books.
Search: 


📙 Adhesion G Protein-coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease by Tobias Langenhan, Torsten Schöneberg (eds.) — download pdf


Latest research on Adhesion GPCRs has unearthed surprising revelations about the events that govern the signal transduction of these receptor molecules and the cellular and organ requirements for these signals. Unexpected and unprecedented findings suggest that Adhesion GPCRs constitute a group of receptors that sense mechanical stimuli and transcode them into metabotropic signals through the action of a novel activation paradigm. Interdisciplinary efforts transcending many areas of biomedical research including pharmacology, physiology, genetics, cell biology, structural biology, biochemistry and bioinformatics were necessary to unveil these fundamental properties. The scientific leaders in the field that carried this research effort have teamed up here to provide a comprehensive overview of our current understanding, how Adhesion GPCRs signal and how these receptors shape organ structure and function.



About book:

About file:

  • File size: 11 096 949
  • Format: pdf


Security code:
Download button

Similar books results


G Protein-coupled Receptors: Molecular Pharmacology From Academic Concept to Pharmaceutical Research
G Protein-coupled Receptors: Molecular Pharmacology From Academic Concept to Pharmaceutical Research epub download by Georges Vauquelin, Bengt von Mentzer

G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety...

Understanding G Protein-coupled Receptors and their Role in the CNS (The Molecular and Cellular Neurobiology Series)
Understanding G Protein-coupled Receptors and their Role in the CNS (The Molecular and Cellular Neurobiology Series) pdf free by Menelas Pangalos, Ceri H. Davies

Pharmacological and molecular cloning studies have shown that the superfamily of G-protein coupled receptors (GPCRs) forms one of the largest and most diverse protein families in nature. They are involved in the modulation of almost all our bodily functio...

G Protein-Coupled Receptors: Structure, Signaling, and Physiology
G Protein-Coupled Receptors: Structure, Signaling, and Physiology free pdf by Sandra Siehler, Graeme Milligan

This text provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membra...

G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, Volume 24
G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, Volume 24 epub download by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers(eds.)

With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The in...

G Protein-Coupled Receptors in Drug Discovery
G Protein-Coupled Receptors in Drug Discovery epub download by Richard M. Eglen, Terry Reisine (auth.), Wayne R. Leifert (eds.)

The G protein-coupled receptors (GPCRs), known to be one of the largest superfamilies in the human genome, underpin a multitude of physiological processes and represent a significant target for bioactive and drug discovery programs. In G Protein-Coupled R...

Ligand Design for G Protein-coupled Receptors
Ligand Design for G Protein-coupled Receptors free download by Didier Rognan, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a ration...

G Protein-Coupled Receptors: Essential Methods
G Protein-Coupled Receptors: Essential Methods free pdf by David Poyner, Mark Wheatley

G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be ...

G Protein-Coupled Receptors: From Structure to Function
G Protein-Coupled Receptors: From Structure to Function free pdf by Jesús Giraldo, Jean-Philippe Pin

G protein-coupled receptors (GPCRs) are the largest family of cell-surface receptors, with more than 800 members identified thus far in the human genome. They regulate the function of most cells in the body, and represent approximately 3% of the genes in ...

G Protein-Coupled Receptors
G Protein-Coupled Receptors pdf free by Tiina P. Iismaa Ph.D., Trevor J. Biden Ph.D., John Shine Ph.D. (auth.)

This book is about the recent advances in the structural and functional characterization of receptors that influence intracellular signalling events through interaction with intracellular GTP-binding proteins (G proteins). Molecular cloning of members of ...